About 60 percent to 70 percent of people with diabetes develop some form of nerve damage (neuropathy), though they may experience no symptoms. Neuropathy typically develops slowly. The best way to prevent this condition is to maintain good control of blood glucose, which can decrease the risk of neuropathy by 60 percent.
Diabetes can cause three types of neuropathy: peripheral neuropathy, mononeuropathy and autonomic neuropathy. Most common is peripheral neuropathy, a slow, progressive loss of function of the sensory nerves in the limbs that causes numbness, tingling and pain in the legs and hands on both sides of the body.
Mononeuropathy, which results from disruption of the blood supply to one or more nerves, leads to the sudden onset of pain or weakness in the area of the body served by the affected nerve.
Autonomic neuropathy damages nerves to the digestive tract, bladder, heart and other internal organs.
Nerve damage from peripheral or autonomic neuropathy is irreversible, but mononeuropathies usually resolve within six months.